Today I'm going to introduce you to a 10-year-old girl who is already making an impact on the world. Her name is ANNABELLE HELD, and she started a dog treat business -- but instead of keeping the profits, she donates them to an animal shelter in her hometown of Marietta, Georgia! Then, my friend, the hilarious DAVID SPADE, is also doing an amazing thing. He's been a big supporter of firefighters here in L.A., especially after the wildfires of about two months ago. To thank them for their hard work, he's inviting hundreds of firefighters to a free comedy show later this month. He'll be here to tell me more about this really cool event. Also, JOHN C. REILLY will be here for the first time! I can't believe he hasn't been here yet, but today the talented actor will finally chat with me. He's been in some of the best movies, like "Chicago," "Gangs of New York" and "The Hours," and now he's in the new movie "Cirque du Freak: The Vampire's Assistant" -- which I can't wait to hear about. And, if you haven't heard MIKA, you'll want to see him on today's show. He's from London, and after his first album he was compared with Freddie Mercury, Elton John and Prince. He just released his second album, "The Boy Who Knew Too Much," and will perform his hit "Blame It on the Girls" for me.